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Analyt Biochem 1979;95:3518

Tirzepatide, the active ingredient in Lillys Mounjaro and Zepbound, works similarly while also acting on another class of receptors known as gastric inhibitory polypeptide (GIP) receptors

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JHU083 has also demonstrated excellent therapeutic efficacy in preclinical models of IDH-mutant gliomas and significantly reduces mTOR signaling (Yamashita et al., 2021)